兔抗CDH23多克隆抗體

Background:

This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.

Applications:

ELISA, IHC

Name of antibody:

CDH23

Immunogen:

Synthetic peptide of human CDH23

Full name:

cadherin-related 23

Synonyms:

USH1D; CDHR23

SwissProt:

Q9H251

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100