中文名稱: XRCC4 抗原(重組蛋白)
英文名稱: XRCC4 Antigen (Recombinant Protein)
別 名: X-ray repair cross complementing 4; SSMED
儲 存: 冷凍(-20℃)
相關(guān)類別:抗原
概 述
Full name: |
X-ray repair cross complementing 4 |
Synonyms: |
SSMED |
Swissprot: |
Q13426 |
Gene Accession: |
BC016314 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. |