小鼠抗ECT2單克隆抗體

Background:

The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].

Applications:

WB, IHC

Name of antibody:

ECT2

Immunogen:

Fusion protein of human ECT2

Full name:

epithelial cell transforming 2 (ECT2), transcript variant 3

Synonyms:

ARHGEF31

SwissProt:

Q9H8V3

IHC positive control:

adenocarcinoma of human ovary tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

104 kDa

WB Positive control:

MCF7 cell lysate

WB Recommended dilution:

500-2000