小鼠抗MAP1LC3A單克隆抗體

Background:

MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.

Applications:

WB, IHC

Name of antibody:

MAP1LC3A

Immunogen:

Fusion protein of human MAP1LC3A

Full name:

microtubule-associated protein 1 light chain 3 alpha

Synonyms:

LC3; LC3A; ATG8E; MAP1ALC3; MAP1BLC3

SwissProt:

Q9H492

IHC positive control:

Human liver cancer and Human gastric cancer

IHC Recommend dilution:

100-500

WB Predicted band size:

14 kDa

WB Positive control:

Mouse brain tissue, Human cerebrum tissue lysates

WB Recommended dilution:

1000-5000