兔抗HGH1多克隆抗體

Background:

HGH1, is also known as BRP16, Brp16 is a 256 amino acid protein encoded by a gene on human chromosome 8. Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Applications:

ELISA, IHC

Name of antibody:

HGH1

Immunogen:

Synthetic peptide of human HGH1

Full name:

HGH1 homolog

Synonyms:

BRP16; BRP16L; FAM203A; FAM203B; C8orf30A; C8orf30B

SwissProt:

Q9BTY7

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

30-150