兔抗HNRNPAB多克隆抗體

Background:

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

HNRNPAB

Immunogen:

Synthetic peptide of human HNRNPAB

Full name:

heterogeneous nuclear ribonucleoprotein A/B

Synonyms:

ABBP1; HNRPAB

SwissProt:

Q99729

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

20-100

WB Predicted band size:

36 kDa

WB Positive control:

Jurkat cell lysate

WB Recommended dilution:

200-1000