兔抗IFIT5多克隆抗體

Background:

Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.

Applications:

WB

Name of antibody:

IFIT5

Immunogen:

Synthesized peptide derived from internal of human IFIT5.

Full name:

interferon-induced protein with tetratricopeptide repeats 5

Synonyms：

P58; RI58

SwissProt:

Q13325

WB Predicted band size:

56 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000