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  • AGTR1抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW9249
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱(chēng):AGTR1抗原(重組蛋白)

英文名稱(chēng):
AGTR1 Antigen (Recombinant Protein)

儲(chǔ)       存:
冷凍(-20℃)

相關(guān)類(lèi)別:抗原


概述

Fusion protein corresponding to a region derived from 300-359 amino acids of human AGTR1


技術(shù)規(guī)格

Full name:

angiotensin II receptor type 1

Synonyms:

AT1; AG2S; AT1B; AT1R; AT1AR; AT1BR; AT2R1; HAT1R; AGTR1B

Swissprot:

P30556

Gene Accession:

BC022447

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.