兔抗IKBKG(Phospho-Ser376) 多克隆抗體

Background:

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

Applications:

IHC

Name of antibody:

IKBKG(Phospho-Ser376)

Immunogen:

Peptide sequence around phosphorylation site of Serine 376(Y-L-S(p)-S-P) derived from Human IKK-γ.

Full name:

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

Synonyms：

IP; IP1; IP2; FIP3; IPD2; NEMO; FIP-3; Fip3p; IMD33; AMCBX1; ZC2HC9; IKK-gamma

SwissProt:

Q9Y6K9

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100