兔抗ACE多克隆抗體

Background:

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

Applications:

ELISA, WB, IHC

Name of antibody:

ACE

Immunogen:

Synthetic peptide of human ACE

Full name:

angiotensin I converting enzyme

Synonyms：

DCP; ICH; ACE1; DCP1; CD143; MVCD3

SwissProt:

P12821

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human cervical cancer and Human breast cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

150 kDa

WB Positive control:

Human ileum adenocarcinoma tissue, Human testis and prostate tissue

WB Recommended dilution:

200-1000