兔抗KIRREL2多克隆抗體

Background:

This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter.

Applications:

ELISA, WB

Name of antibody:

KIRREL2

Immunogen:

Fusion protein of human KIRREL2

Full name:

kirre like nephrin family adhesion molecule 2

Synonyms:

NLG1; NEPH3; FILTRIN

SwissProt:

Q6UWL6

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

75 kDa

WB Positive control:

Hela cells

WB Recommended dilution:

200-1000