兔抗LILRB2多克隆抗體

Background:

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

LILRB2

Immunogen:

Fusion protein of human LILRB2

Full name:

leukocyte immunoglobulin like receptor B2

Synonyms:

ILT4; LIR2; CD85D; ILT-4; LIR-2; MIR10; MIR-10

SwissProt:

Q8N423

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human lung cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

65 kDa

WB Positive control:

Hela cell, Raji cell, HepG2 cell lysates

WB Recommended dilution:

500-2000