小鼠抗SHPK單克隆抗體

Background:

The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq, Jul 2008].

Applications:

WB, IF

Name of antibody:

SHPK

Immunogen:

Fusion protein of human SHPK

Full name:

sedoheptulokinase (SHPK)

Synonyms:

CARKL; SHK

SwissProt:

Q9UHJ6

WB Predicted band size:

51 kDa

WB Positive control:

HepG2, SVT2 cell lysates

WB Recommended dilution:

200-1000