兔抗PRKAG1多克隆抗體

Background:

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Applications:

ELISA, WB

Name of antibody:

PRKAG1

Immunogen:

Synthetic peptide of human PRKAG1

Full name:

protein kinase, AMP-activated, gamma 1 non-catalytic subunit

Synonyms：

AMPKG

SwissProt:

P54619

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

38 kDa

WB Positive control:

Human fetal liver tissue

WB Recommended dilution:

200-1000