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  • ELOB抗原(重組蛋白)

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    數(shù)量:

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17191
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱(chēng):  ELOB抗原(重組蛋白)

英文名稱(chēng): ELOB Antigen (Recombinant Protein)

別      名: SIII; TCEB2

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概  述:

Fusion protein corresponding to a region derived from 1-118 amino acids of human ELOB


技術(shù)規(guī)格:

Full name:

elongin B

Synonyms:

SIII; TCEB2

Swissprot:

Q15370

Gene Accession:

BC013306

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, Aug 2008]