兔抗ALK(Phospho-Tyr1096) 多克隆抗體

Background:

This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer.

Applications:

IHC

Name of antibody:

ALK(Phospho-Tyr1096)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 1096 (P-N-Y(p)-C-F) derived from Human ALK.

Full name:

anaplastic lymphoma receptor tyrosine kinase

Synonyms：

CD246; NBLST3

SwissProt:

Q9UM73

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100