中文名稱:MAP4K2抗原(重組蛋白)
英文名稱: MAP4K2 Antigen (Recombinant Protein)
別 名: GCK; BL44; RAB8IP
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human MAP4K2 |
Full name: |
mitogen-activated protein kinase kinase kinase kinase 2 |
Synonyms: |
GCK; BL44; RAB8IP |
Swissprot: |
Q12851 |
Gene Accession: |
BC047865 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. |