兔抗ANAPC2多克隆抗體

Background:

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.

Applications:

ELISA, IHC

Name of antibody:

ANAPC2

Immunogen:

Fusion protein of human ANAPC2

Full name:

anaphase promoting complex subunit 2

Synonyms：

APC2; RP11-350O14.5

SwissProt:

Q9UJX6

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer and human liver cancer

IHC Recommend dilution:

50-200