兔抗EFHD2多克隆抗體

Background:

EFHD2 is a calcium-binding adaptor protein associated with pathologically aggregated tau in Alzheimer disease brain and in a mouse model of frontotemporal dementia. EFHD2 has cell type-specific functions, including modulation of intracellular calcium responses, actin dynamics, and microtubule transport. May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.

Applications:

ELISA, WB

Name of antibody:

EFHD2

Immunogen:

Synthetic peptide of human EFHD2

Full name:

EF-hand domain family member D2

Synonyms:

SWS1

SwissProt:

Q96C19

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

27 kDa

WB Positive control:

A549 cell lysate

WB Recommended dilution:

200-1000