NDP抗原（重組蛋白）

Full name:

Norrie disease (pseudoglioma)

Synonyms:

ND; EVR2; FEVR

Swissprot:

Q00604

Gene Accession:

BC029901

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in this gene result in Norrie disease and X-linked exudative vitreoretinopathy.