兔抗NR4A3多克隆抗體

Background:

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

NR4A3

Immunogen:

Synthesized peptide derived from internal of human NR4A3.

Full name:

nuclear receptor subfamily 4, group A, member 3

Synonyms：

CHN; TEC; CSMF; NOR1; MINOR

SwissProt:

Q92570

WB Predicted band size:

68 kDa

WB Positive control:

COLO cells lysate

WB Recommended dilution:

500-3000