兔抗PRKAG2多克隆抗體

Background:

AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Applications:

ELISA, WB, IHC

Name of antibody:

PRKAG2

Immunogen:

Fusion protein of human PRKAG2

Full name:

protein kinase AMP-activated non-catalytic subunit gamma 2

Synonyms:

AAKG; CMH6; WPWS; AAKG2; H91620p

SwissProt:

Q9UGJ0

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

50-300

WB Predicted band size:

63 kDa

WB Positive control:

Mouse heart tissue lysate

WB Recommended dilution:

200-1000