兔抗SSB多克隆抗體

Background:

The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus.

Applications:

ELISA, WB, IHC

Name of antibody:

SSB

Immunogen:

Synthetic peptide of human SSB

Full name:

Sjogren syndrome antigen B (autoantigen La)

Synonyms：

La; LARP3; La/SSB

SwissProt:

P05455

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer and Human ovarian cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

47 kDa

WB Positive control:

K562, 231, Raji and hela cells

WB Recommended dilution:

500-2000