兔抗STAT4 (Phospho-Tyr693) 多克隆抗體

Background:

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

Applications:

WB, IHC

Name of antibody:

STAT4 (Phospho-Tyr693)

Immunogen:

Synthetic peptide of human STAT4 (Phospho-Tyr693)

Full name:

signal transducer and activator of transcription 4 (Phospho-Tyr693)

Synonyms：

SLEB11

SwissProt:

Q14765

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

86 kDa

WB Positive control:

HepG2 cells treated with IL-4

WB Recommended dilution:

500-1000