中文名稱(chēng):兔抗BTK(Phospho-Tyr223)多克隆抗體
Background: |
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Applications: |
WB |
Name of antibody: |
BTK(Phospho-Tyr223) |
Immunogen: |
Peptide sequence around phosphorylation site of tyrosine 223 (A-L-Y(p)-D-Y) derived from Human BTK. |
Full name: |
Bruton agammaglobulinemia tyrosine kinase |
Synonyms: |
AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1 |
SwissProt: |
Q06187 |
WB Predicted band size: |
76 kDa |
WB Positive control: |
Hela cells lysates treated with serum |
WB Recommended dilution: |
500-1000 |