兔抗CAPN7多克隆抗體

Background:

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity.

Applications:

ELISA, WB, IHC

Name of antibody:

CAPN7

Immunogen:

Fusion protein of human CAPN7

Full name:

calpain 7

Synonyms：

PALBH; CALPAIN7

SwissProt:

Q9Y6W3

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

93 kDa

WB Positive control:

Human normal liver and mouse liver tissue, mouse intestines and pancreas tissue, hepg2 and HT-29 cells, mouse heart tissue

WB Recommended dilution:

500-2000