兔抗CCNH多克隆抗體

Background:

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes.

Applications:

ELISA, WB

Name of antibody:

CCNH

Immunogen:

Synthetic peptide of human CCNH

Full name:

cyclin H

Synonyms：

CAK; p34; p37; CycH

SwissProt:

P51946

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

38 kDa

WB Positive control:

231，Raji and K562 cell

WB Recommended dilution:

200-1000