兔抗CENPE多克隆抗體

Background:

Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.

Applications:

ELISA, WB, IHC

Name of antibody:

CENPE

Immunogen:

Synthetic peptide of human CENPE

Full name:

centromere protein E

Synonyms:

KIF10; CENP-E; MCPH13; PPP1R61

SwissProt:

Q02224

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-100

WB Predicted band size:

316 kDa

WB Positive control:

Human vermiform appendix tissue lysate

WB Recommended dilution:

200-1000