小鼠抗EXOC4單克隆抗體

Background:

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Applications:

WB

Name of antibody:

EXOC4

Immunogen:

Fusion protein of human EXOC4

Full name:

exocyst complex component 4

Synonyms:

SEC8; Sec8p; SEC8L1

SwissProt:

Q96A65

WB Predicted band size:

110 KD

WB Positive control:

293T cell lysate

WB Recommended dilution:

500-2000