兔抗HNRNPF多克隆抗體

Background:

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Applications:

ELISA, WB

Name of antibody:

HNRNPF

Immunogen:

Synthetic peptide of human HNRNPF

Full name:

heterogeneous nuclear ribonucleoprotein F

Synonyms：

HNRPF; mcs94-1; OK/SW-cl.23

SwissProt:

P52597

ELISA Recommended dilution:

2000-10000

WB Predicted band size:

46 kDa

WB Positive control:

Human bladder cancer tissue, A375, K562, Hela and HepG2 cells

WB Recommended dilution:

500-2000