兔抗IFITM2多克隆抗體

Background:

IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.

Applications:

ELISA, IHC

Name of antibody:

IFITM2

Immunogen:

Fusion protein of human IFITM2

Full name:

interferon induced transmembrane protein 2

Synonyms:

1-8D; DSPA2c

SwissProt:

Q01629

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human brain

IHC Recommend dilution:

30-150