兔抗INSIG2多克隆抗體

Background:

The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.

Applications:

ELISA, IHC

Name of antibody:

INSIG2

Immunogen:

Fusion protein of human INSIG2

Full name:

insulin induced gene 2

SwissProt:

Q9Y5U4

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human esophagus cancer and human brain

IHC Recommend dilution:

25-100