兔抗S1PR5多克隆抗體

Background:

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.

Applications:

ELISA, IHC

Name of antibody:

S1PR5

Immunogen:

Synthetic peptide of human S1PR5

Full name:

sphingosine-1-phosphate receptor 5

Synonyms:

EDG8; S1P5; Edg-8; SPPR-1; SPPR-2

SwissProt:

Q9H228

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human brain

IHC Recommend dilution:

20-100