兔抗BCL10多克隆抗體

Background:

This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma.

Applications:

ELISA, WB, IHC

Name of antibody:

BCL10

Immunogen:

Fusion protein of human BCL10

Full name:

B-cell CLL/lymphoma 10

Synonyms：

CLAP; mE10; CIPER; c-E10; CARMEN

SwissProt:

O95999

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

26 kDa

WB Positive control:

Hela cells

WB Recommended dilution:

500-2000