兔抗CASP7多克隆抗體

Background:

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

CASP7

Immunogen:

Fusion protein of human CASP7

Full name:

caspase 7, apoptosis-related cysteine peptidase

Synonyms：

MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3

SwissProt:

P55210

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human liver cancer and human lung cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

34 kDa

WB Positive control:

Mouse brain tissue

WB Recommended dilution:

200-1000