SERPINB4 抗原（重組蛋白）

Full name:

serpin family B member 4

Synonyms:

PI11; SCCA1; SCCA2; LEUPIN; SCCA-2

Swissprot:

P48594

Gene Accession:

BC017401

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation.