小鼠抗JAG1單克隆抗體

Background:

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Applications:

WB

Name of antibody:

JAG1

Immunogen:

Fusion protein of human JAG1

Full name:

jagged 1

Synonyms:

AGS; AHD; AWS; HJ1; AGS1; CD339; JAGL1

SwissProt:

P78504

WB Predicted band size:

134 KD

WB Positive control:

HepG2 cell lysate

WB Recommended dilution:

500-2000