兔抗IMPDH2多克隆抗體

Background:

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Applications:

ELISA, WB, IHC

Name of antibody:

IMPDH2

Immunogen:

Fusion protein of human IMPDH2

Full name:

IMP (inosine 5'-monophosphate) dehydrogenase 2

Synonyms：

IMPD2; IMPDH-II

SwissProt:

P12268

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human lung cancer and human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

56 kDa

WB Positive control:

A549 cells

WB Recommended dilution:

500-2000